Events Calendar

Workshop on Dynamic properties of brain states and their transitions

From : Tuesday 06 July 2021 - 15:00

To     : Wednesday 07 July 2021 - 17:15

Workshop organized for OCNS.

Dynamic properties of brain states and their transitions


July 6th Paris: 3pm-6:15pm; New York 9am-12:15pm;  L.A. 6am-9:15am

July 7th Paris: 2pm-5:15pm; New York 8am-11:15pm;  L.A. 5am-8:15am


organized by:

Alain Destexhe       (CNRS, Paris, France)

Jennifer Goldman  (CNRS, Paris, France)

Alessandra Camassa      (Institute of Biomedical Research August Pi i Sunyer, Barcelona, Spain)

Mavi Sanchez-Vives       (Institute of Biomedical Research August Pi i Sunyer, Barcelona, Spain)


Computational neuroscience offers insights into the dynamical properties of the brain under different states of awareness. The classification of brain states is relevant not only for the multiscale investigation of circuits and full brain networks, but also clinically relevant for the diagnosis (and eventual treatment) of disorders of sleep and consciousness, and to identify novel targets for anesthesia.

The temporal and spatial features of activity patterns generated by the brain under different states provide information about the computations carried out by the brain during different states, and the mechanisms and dynamics underlying transitions across states. The joint effort of experimentalists and computational neuroscientists results in electrophysiological, imaging, and simulated data that span space-time scales, to provide unique insights into brain dynamics and novel explanations of observed phenomena, providing new possibilities for overcoming experimental limitations.

In this workshop we bring together a wide range of experimental and clinical approaches, analysis techniques and computational models, generating multimodal and multiscale data and simulations to characterize the spontaneous spatiotemporal activity of the brain, its responsiveness, complexity, and dynamical properties under different brain states. We also open to floor to discuss which are the main open questions in the field.



JULY 6TH 2021

15:00 Welcome and introduction by the organizers.


Session 1 Chair Jennifer Goldman

15:10 Mavi Sanchez-Vives (Institute of Biomedical Research August Pi i Sunyer, Barcelona, Spain) “Complexity across experimental brain states: measures and mechanisms”

15:35 Albrecht Stroh (University of Mainz, Germany) “Brain states govern the spatio-temporal dynamics of resting-state functional connectivity”

16:00 Keynote David McCormick (University of Oregon, USA) “Rapid Dynamics Explain Neuronal and Behavioral Variability”

16:40 Coffee break


Session 2 Chair Alain Destexhe

16:50 Marcello Massimini (University of Milan, Italy) ”State-dependent changes in cortical differentiation are due to neuronal OFF-periods”

17:15 Alessandra Camassa (Institute of Biomedical Research August Pi i Sunyer, Barcelona, Spain) “The metastability of the  cortical Down states and its role in the dynamics of the unconscious brain”

17:40 Morten L Kringelbach (University of Oxford,UK ) “"Rare long-range cortical exceptions enhance information processing in turbulent brain dynamics”

18:05 Viktor Jirsa (CNRS, Marseille, France) “Symmetry breaking shapes invariance of brain state dynamics at rest”

17:15 end of first day



Day 2 JULY 7TH 2021


Session 3 Chair Alessandra Camassa

14:00 Alessandro Arena (University of Oslo, Norway) "Cortical responsiveness and complexity in rats across brain states"

14:25 Maurizio Mattia (Istituto Superiore di Sanita,  Rome, Italy) “Probing the edge of synchronization: Slow-waves onset in premotor cortex of behaving monkeys”

14:50 Keynote Gustavo Deco (University Pompeu Fabra, Barcelona, Spain) "The arrow of time in brain dynamics: non-equilibrium in different brain states"

15:30 Coffee break


Session 4 Chair Mavi Sanchez-Vives

15:40 Cristiano Capone (INFN, Rome, Italy) "Simulations Approaching Data: Cortical Slow Waves in Inferred Models of the Whole Hemisphere of Mouse"

16:05 Alain Destexhe (CNRS, Paris, France) “Building mean-field models from microscopic scales to account for mesoscopic and macroscopic-scale phenomena”.

16:30 Jennifer Goldman (CNRS, Paris, France) “Novel methods illustrate the emergence of global brain states from microscopic mechanisms to identify new interpretations of neural information.”

16:55 Round table: Where are we in the multiscale understanding of brain states? What are the main open questions? What computer models and simulations would be needed? How to transfer this knowledge to the clinic?

17:30 End of session